ARCHIVES
VOL. 1, ISSUE 1 (2025)
Development and validation of a novel extraction method for bioactive compounds from pharmaceutical plants
Authors
Dr. Amina N Kijana
Abstract
Pharmaceutical plants are a vital source of bioactive compounds with
therapeutic potential, but their efficient extraction remains a significant
challenge. Conventional extraction methods often involve lengthy procedures,
high solvent consumption, and limited selectivity, which can reduce yield and
compromise compound integrity. This study aimed to develop and validate a novel
extraction method that enhances the recovery of bioactive compounds from
selected pharmaceutical plants. The proposed method employed a combination of
optimized solvent systems and advanced extraction techniques to maximize yield
while preserving the chemical integrity of target compounds. Validation was
conducted following international guidelines, assessing parameters such as
accuracy, precision, reproducibility, extraction efficiency, and selectivity.
Experimental trials were performed on multiple plant samples known for their
pharmacological activity, and the resulting extracts were analyzed using
chromatographic and spectrophotometric methods. The findings demonstrated that
the novel extraction protocol significantly improved bioactive compound yield
compared to traditional methods, with higher reproducibility and reduced
solvent usage. Statistical analyses confirmed the method’s precision and
reliability, indicating its suitability for routine phytochemical studies and
pharmaceutical applications. These results highlight the potential of the
optimized extraction approach to facilitate the isolation of therapeutic
compounds and support drug discovery processes. In conclusion, the developed
method offers a robust, efficient, and environmentally considerate alternative
to conventional extraction techniques, providing a practical tool for
researchers and industry professionals aiming to harness the medicinal
properties of plant-derived compounds. Future studies could explore scaling up
the procedure and applying it to a broader range of plant species.
Download
Pages:29-35
How to cite this article:
Dr. Amina N Kijana "Development and validation of a novel extraction method for bioactive compounds from pharmaceutical plants". World Journal of Pharmaceutical, Vol 1, Issue 1, 2025, Pages 29-35
Download Author Certificate
Please enter the email address corresponding to this article submission to download your certificate.